At Corium Clinic, Polynucleotide treatments offer an advanced, science-led approach to skin rejuvenation, hair restoration, and tissue regeneration. Designed to repair, hydrate, and regenerate the skin and scalp at a cellular level, this innovative injectable treatment improves overall skin and scalp quality while delivering natural, long-lasting results.
Polynucleotides frequently referred to as PDRN (Polydeoxyribonucleotide), are naturally occurring nucleic acid fragments extracted from salmon or trout DNA through a specialised extraction. These molecules possess remarkable regenerative properties, capable of stimulating tissue repair, enhancing collagen synthesis, and promoting cellular proliferation.
When administered they exert their rejuvenating effects at the cellular level. By stimulating fibroblast activity and enhancing extracellular matrix production, polynucleotides help restore the skin’s elasticity, improve texture, and promote hair growth, resulting in a more vibrant and youthful appearance
When used in aesthetic treatments, these highly purified molecules stimulate the skin’s natural healing processes and improve overall skin function.
Unlike traditional dermal fillers, polynucleotides do not add volume. Instead, they work by enhancing skin or scalp quality from within, making them ideal for subtle, natural rejuvenation.
30-Min
2-3 Months
Minimal - Mild
Hours to Days
3-4 sessions, 2-3 weeks apart for initial course
From £250
When administered via injection or topical application, polynucleotides penetrate deep into the skin or scalp, where they exert their rejuvenating effects at the cellular level.
This process helps to:
Over time, this results in smoother, firmer, and healthier-looking skin.
This versatile treatment can address a wide range of skin concerns, including:
Polynucleotides are suitable for delicate areas and can be used on the face, neck, décolletage, under-eye area, and even hands.
Deep Skin and Scalp Regeneration
Supports natural tissue repair and long-term skin and scalp health.
Improved Skin Quality
Enhances texture, tone, and overall radiance.
Collagen Stimulation
Boosts firmness and elasticity for a youthful appearance.
Hydration Boost
Improves moisture retention for plumper, healthier skin.
Natural Results
Delivers subtle, refreshed results without altering facial structure.
Minimal Downtime
Quick treatment with little recovery time required.
Consultation
Your practitioner will assess your skin and discuss your concerns and goals.
Procedure
Small injections or a fine cannula are administered into targeted areas using a precise technique.
Treatment Plan
A course of 4 sessions is typically recommended, spaced a few weeks apart for optimal results.
Results
Initial improvements may be seen within a few weeks, with continued enhancement as collagen production increases. Results can last several months depending on your skin and lifestyle.
Polynucleotide treatments are ideal for:
At Corium Clinic, we combine innovation with expertise to deliver treatments that enhance your skin’s health and confidence.
Yes, they are considered safe when performed by qualified professionals.
Treatments are typically well-tolerated, with minimal discomfort reported by most patients. Numbing cream can be used to ensure comfort
Typically, 3–4 sessions are recommended for optimal results
You may experience mild redness, swelling, or bruising at injection sites, which usually resolves within hours to days
Biostimulation Treatment to Kick-Start Skin Regeneration – Boost Collagen, Hydration & Skin Elasticity Naturally